El éxito del ISIC, de su credibilidad como documento de acreditación y de sus servicios asociados, ventajas y descuentos proviene de su reconocimiento internacional y local de organizaciones entre otras, como:
Relación de Instituciones y/o Organizaciones que avalan el carné ISIC
| ALCANCE | ORGANIZACIÓN |
| Global | UNESCO-United Nations Educational Scientific and Cultural Organisation |
| Global | CAN-Community of Andean Nations |
| Global | European Students’ Union |
| Global | International Association of Universities |
| Global | European Law Students’ Association |
| Global | European Commission (Directorate-General for Education and Cultural) |
| Global | Europe_International Air Rail Organisation |
| Global | AIESEC |
| Global | United World Colleges |
| Global | World Youth Student Education Travel Confederation (WYSE) |
| Global | United Nation World Tourism Organisation |
| ALCANCE | ORGANIZACIÓN |
| Global | Microsoft |
| Global | E-Academy/on the hub |
| Global | Hostelling International |
| Global | Welcome Letter ISIC as Affiliate Member of UNWTO |
| Global | Mastercard |
| Global | World Savings Bank Institute |
| Global | Education First |
| Global | Global International Pharmaceutical Students Federation |
| Global | Economist |
| Global | Accor |
| Global | Eventim |